FORMULATION AND EVALUATION OF MEDICATED CHEWING GUM PDF

Abstract: The medicated chewing gum containing methyl prednisolone IP may be an excellent formulation to treat oral ulcer caused by the consumption of. An attempt has been made to formulate new chewing gum device for metaclopramide in the form of tablet. The new drug delivery system was obtained , at room. Formulation and evaluation of medicated chewing gum as antiplaque and antibacterial agent. S Vasudha Lakshmi1, Hemant KS Yadav1*, KP Mahesh2, Swati.

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Home Publications Conferences Register Contact. Drug release from a dosage form is the critical step in drug absorption and bioavailability, thus an experimental work has been designed to evaluate the efficiency of this kind of therapeutic system by verifying its capability to release the drug dose and by assessing the delivery of Dolasetron for bypassing the hepatic first pass effect. Authors are permitted and encouraged frmulation post their work online e.

Simple diffusion into the medium causes the release of only a small percentage of the drug contained in the medicated chewing gum, while the delivery of the major part medicatted the dose occurs during mastication. The in vivo studies on human volunteers were carried out for optimized formulation F5 containing chitosan and antibacterial agent which showed a better reduction in the bacterial count and gingival index.

Pharmaceutica Analytica Acta Open Access. Different formulations of chewing gum with varying concentration of plasticizers like glycerol and castor oil were formulated. Presently he is an M. Motion Sickness Susceptibility, Autonomic Neuroscience: Chewing gum, chitosan, chlorhexidine, dental caries.

Chlorohexidine Gluconate, Scholars Research Library, ; 2: The 5- Hydroxytrytryptamin Receptor Antagonist as Antiementis: Vol 7 No 4 Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution-NonCommercial 3. The prepared gums were evaluated for physical parameters, compatibility studies, drug content, moisture content, stability studies and in vitro drug-release testing.

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Formulation and evaluation of medicated chewing gum of Metaclopramide.

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An attempt has been made to formulate new chewing gum for Dolasetron. An attempt has been made to formulate new chewing gum device for metaclopramide in the form of tablet. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal’s published version of the work e. Abstract An attempt has been made to formulate new chewing gum for Dolasetron.

From this study, we can conclude that the medicated chewing formulation can be a better choice in the coming years which provides several benefits and evaluatiion benefits commercially.

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The new drug delivery system was obtained, at room temperature conventional pharmaceutical equipment. Downloads Download data is not yet available.

Madan N, Rathnam A. The test group administered chewing gums containing chlorhexidine, with and without the polymer, while the control group administered dummy chewing gums.

Publication Policies and Ethics. Evaluatiin carry out in vivo study on humans double-blind, crossover clinical trial was conducted on 18 adult volunteers from Department of Oral Medicine and Radiology, JSS Dental College, Mysore. Skip to main content Skip to main navigation menu Skip to site footer.

The formulation, which contains highest concentration of chitosan, showed more in vitro release compared to other formulation. Authors who publish with this journal agree to the following terms: Volume 7, Issue 4, July-August Chitosan containing chewing gum has a greater formulatipn effect compared with gums containing only chlorhexidine. Agri and Aquaculture Journals Dr. Chewing gumChitosanChlorhexidineDental Caries.

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Formulation And Evaluation Of Medicated Chewing Gum Of Metaclopramide |

As the proportion of gum base was increased, an increase in hardness of the chewing gum was observed. Hence, Metaclopramide chewing gum can be considered as a better formulation for the buccal drug delivery system, in which drug is absorbed buccally and reaches the systemic circulation via jugular vein. Paresh Mohan completed B. Drug release from a dosage form is the critical step in drug absorption and bioavailability, thus an experimental work has been designed to evaluate the efficiency of this kind of therapeutic system by verifying its capability to release the drug dose and by assessing the delivery of Metaclopramide for bypassing the hepatic first pass effect.

Journal of Current Pharma Research ; 4 4: Ezhumlai K, Rajalakshmi A. Paresh is having 3 International review articles and He is attended 1 National conferences in Solan H. Better consistency of formulation and faster release of drug in saliva was obtained with glycerol F IIIand Castor oil F II but castor oil shows optimum result against glycerol combination, which is formulation II. The volunteers were visually examined for presence or absence of gingival erythema, gingival edema and gingival bleeding and the antibacterial activity was assessed by the reduction in bacterial count in the plaque samples.

Different formulations of chewing gum with varying concentration of plasticizers like glycerol and castor oil were formulated.

In the present study, an attempt has been made to formulate the chewing gum of Metaclopramide.